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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
5.45
Human Site:
S80
Identified Species:
10
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
S80
E
K
N
S
V
P
L
S
D
A
L
L
N
K
L
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
S80
E
K
N
S
V
P
L
S
D
A
L
L
N
K
L
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
L70
E
D
W
L
S
L
L
L
K
L
E
K
N
S
V
Dog
Lupus familis
XP_539016
855
96614
N80
E
K
N
S
V
P
L
N
D
A
L
L
N
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
N76
E
K
N
S
S
P
L
N
D
D
L
L
N
K
L
Rat
Rattus norvegicus
NP_001101642
835
94323
N76
E
K
N
S
P
P
L
N
D
A
L
L
N
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
N80
E
K
N
G
V
L
Q
N
D
G
L
L
N
K
L
Chicken
Gallus gallus
XP_419867
879
99691
D84
K
K
G
I
P
Q
M
D
L
S
I
L
N
R
L
Frog
Xenopus laevis
NP_001082090
882
99060
D81
N
T
G
L
P
Q
I
D
P
Q
L
L
N
K
L
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
G140
A
Q
F
E
L
L
Q
G
N
M
K
K
C
T
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
A82
R
E
A
S
R
T
V
A
S
N
V
D
P
T
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
S68
T
S
I
G
P
R
R
S
V
A
P
Q
R
Q
A
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
H56
A
S
E
I
L
S
S
H
N
N
D
K
I
A
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
93.3
N.A.
80
86.6
N.A.
66.6
26.6
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
86.6
93.3
N.A.
73.3
60
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
0
0
0
0
8
0
39
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
0
0
0
0
0
16
47
8
8
8
0
0
0
% D
% Glu:
54
8
8
8
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
16
16
0
0
0
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
16
0
0
8
0
0
0
8
0
8
0
0
% I
% Lys:
8
54
0
0
0
0
0
0
8
0
8
24
0
54
0
% K
% Leu:
0
0
0
16
16
24
47
8
8
8
54
62
0
0
62
% L
% Met:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
8
% M
% Asn:
8
0
47
0
0
0
0
31
16
16
0
0
70
0
8
% N
% Pro:
0
0
0
0
31
39
0
0
8
0
8
0
8
0
0
% P
% Gln:
0
8
0
0
0
16
16
0
0
8
0
8
0
8
0
% Q
% Arg:
8
0
0
0
8
8
8
0
0
0
0
0
8
8
0
% R
% Ser:
0
16
0
47
16
8
8
24
8
8
0
0
0
8
0
% S
% Thr:
8
8
0
0
0
8
0
0
0
0
0
0
0
16
8
% T
% Val:
0
0
0
0
31
0
8
0
8
0
8
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _